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心脏横纹肌肉瘤:一项临床病理与电子显微镜研究

Cardiac rhabdomyosarcoma: a clinicopathologic and electron microscopy study.

作者信息

Attanasio A, Romitelli S, Mauriello A, Palmieri G, Stefani A, Pierangeli L

机构信息

Dipartimento di Medicina Interna, Università degli Studi Tor Vergata, Roma.

出版信息

G Ital Cardiol. 1998 Apr;28(4):383-6.

PMID:9616853
Abstract

A 66-year-old woman was admitted to the hospital with a neurological syndrome characterized by ataxia and diplopia. Magnetic resonance of the brain documented an ischemic medullary lesion. Examination of the heart revealed a grade 2/6 systolic murmur at the left sternal border and apex that radiated towards the axilla. The echocardiography study showed a mild mitral regurgitation, and an abnormally enlarged posterior papillary muscle was found in the left ventricle. Two weeks after admission, the patient died suddenly due to a stroke. At autopsy, a recent vast swollen ischemic cerebral infraction was found. Furthermore, two old infarcts were observed in the spleen. A cardiac examination showed a white-gray ulcered mass in the left ventricle and histological analysis revealed a rhabdomyosarcoma.

摘要

一名66岁女性因以共济失调和复视为特征的神经综合征入院。脑部磁共振成像显示延髓有缺血性病变。心脏检查发现左胸骨缘和心尖处有2/6级收缩期杂音,并向腋窝传导。超声心动图检查显示轻度二尖瓣反流,左心室发现后乳头肌异常增大。入院两周后,患者因中风突然死亡。尸检发现近期有大片肿胀的缺血性脑梗死。此外,脾脏发现两处陈旧性梗死。心脏检查发现左心室有一个灰白色溃疡肿块,组织学分析显示为横纹肌肉瘤。

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