Sato M, Nagai H, Kurasima A, Yotsumoto H, Mohri M, Tanaka K, Fukushima K, Hebisawa A
Department of Pulmonology, Tokyo National Chest Hospital.
Nihon Kokyuki Gakkai Zasshi. 1998 Feb;36(2):187-91.
A 56-year-old man with pure red cell aplasia (PRCA), hypogammaglobulinemia and mediastinal tumor was admitted to our hospital with of dyspnea, high fever and general fatigue. Chest X-ray showed a large cavity with a niveau in the left lung. Biopsy of the mediastinal tumor revealed an epithelial cell-type thymoma. Lung abscess with Good's syndrome and PRCA was diagnosed. Antibiotics was administered, and percutaneous catheter drainage of the lung abscess was performed. He recovered and was discharged. Hypogammaglobulinemia in the case may have resulted from reduced production of gammaglobulin associated with a quantitative B-cell defect.
一名56岁男性,患有纯红细胞再生障碍性贫血(PRCA)、低丙种球蛋白血症和纵隔肿瘤,因呼吸困难、高热和全身乏力入院。胸部X线显示左肺有一个有液平的大空洞。纵隔肿瘤活检显示为上皮细胞型胸腺瘤。诊断为伴有古德综合征和PRCA的肺脓肿。给予抗生素治疗,并对肺脓肿进行了经皮导管引流。患者康复出院。该病例中的低丙种球蛋白血症可能是由于与B细胞数量缺陷相关的丙种球蛋白产生减少所致。