Bumann D, de Wit M, Beyer W, Beese M, Lübeck M, Bücheler E, Clausen M
Institut für Röntgendiagnostik, Universitäts-Krankenhaus Eppendorf, Hamburg.
Rofo. 1998 May;168(5):457-65. doi: 10.1055/s-2007-1015162.
To determine the value of F-18-FDG-positron emission tomography (FDG-PET) compared with computed tomography (CT) in the staging of malignant lymphomas.
50 patients with biopsy-proven lymphoma were studied with FDG-PET and CT. The results in initial, posttherapeutic and staging of recurrence were compared.
37 of 65 FDG-PET were identical with CT. 28 studies showed differences. 14 post-therapeutically and one of the initial studies led to downstaging by FDG-PET were as upstaging resulted in one case of initial staging. In two cases false positive pulmonary FDG accumulations caused an upstaging.
FDG-PET was at least comparable to CT in recording the extension of a newly diagnosed lymphoma, or its recurrence. Upstaging according to FDG-PET occurred only once in initial staging. FDG-PET plays its most important role in the evaluation of residual mass in CT after therapy by accumulating FDG in viable tumour rather than in fibrotic tissue. 14 cases of downstaging according to FDG-PET resulted.
确定F-18-氟代脱氧葡萄糖正电子发射断层扫描（FDG-PET）与计算机断层扫描（CT）相比在恶性淋巴瘤分期中的价值。
对50例经活检证实为淋巴瘤的患者进行FDG-PET和CT检查。比较初始、治疗后及复发分期的结果。
65例FDG-PET检查结果中，37例与CT相同。28例检查结果存在差异。治疗后14例以及初始检查中的1例经FDG-PET检查后分期降低，而初始分期中有1例分期升高。2例肺部FDG假阳性积聚导致分期升高。
在记录新诊断淋巴瘤的范围或其复发情况方面，FDG-PET至少与CT相当。根据FDG-PET进行的分期升高仅在初始分期中出现过一次。FDG-PET在评估治疗后CT中的残留肿块时发挥着最重要的作用，因为它能使FDG在存活肿瘤而非纤维化组织中积聚。根据FDG-PET有14例分期降低。
