[计算机断层扫描和F-18-FDG正电子发射断层扫描在恶性淋巴瘤分期中的比较]

[Computerized tomography and F-18-FDG positron emission tomography in staging of malignant lymphomas: a comparison].

作者信息

Bumann D, de Wit M, Beyer W, Beese M, Lübeck M, Bücheler E, Clausen M

机构信息

Institut für Röntgendiagnostik, Universitäts-Krankenhaus Eppendorf, Hamburg.

出版信息

Rofo. 1998 May;168(5):457-65. doi: 10.1055/s-2007-1015162.

DOI:10.1055/s-2007-1015162

PMID:9617362

Abstract

PURPOSE

To determine the value of F-18-FDG-positron emission tomography (FDG-PET) compared with computed tomography (CT) in the staging of malignant lymphomas.

MATERIAL AND METHOD

50 patients with biopsy-proven lymphoma were studied with FDG-PET and CT. The results in initial, posttherapeutic and staging of recurrence were compared.

RESULTS

37 of 65 FDG-PET were identical with CT. 28 studies showed differences. 14 post-therapeutically and one of the initial studies led to downstaging by FDG-PET were as upstaging resulted in one case of initial staging. In two cases false positive pulmonary FDG accumulations caused an upstaging.

CONCLUSION

FDG-PET was at least comparable to CT in recording the extension of a newly diagnosed lymphoma, or its recurrence. Upstaging according to FDG-PET occurred only once in initial staging. FDG-PET plays its most important role in the evaluation of residual mass in CT after therapy by accumulating FDG in viable tumour rather than in fibrotic tissue. 14 cases of downstaging according to FDG-PET resulted.

摘要