Zalsman G, Hermesh H, Munitz H
Geha Psychiatric Hospital, Petah Tikva, Israel.
Clin Neuropharmacol. 1998 May-Jun;21(3):201-2.
Benzodiazepine withdrawal delirium is thought to be uncommon. Only two clear reports of alprazolam withdrawal appear in the literature, but the use of this drug is expected to increase because of its recent approval for the treatment of panic disorder. We report on a patient with severe alprazolam withdrawal delirium that developed immediately after an accidental reduction of the dose. This case demonstrates importance of clinician awareness of the previous use of alprazolam in individual patients, especially in hospital settings where free patient use of drugs is prohibited.
苯二氮䓬戒断谵妄被认为并不常见。文献中仅出现过两篇关于阿普唑仑戒断的明确报告,但由于该药最近被批准用于治疗惊恐障碍,预计其使用量将会增加。我们报告一例患者,在意外减少阿普唑仑剂量后立即出现了严重的阿普唑仑戒断谵妄。该病例表明临床医生了解个体患者之前使用阿普唑仑情况的重要性,尤其是在禁止患者自行使用药物的医院环境中。