Kronenberg F
Institute of Medical Biology and Human Genetics, University of Innsbruck, Austria.
Curr Opin Nephrol Hypertens. 1998 May;7(3):271-8. doi: 10.1097/00041552-199805000-00006.
High plasma concentrations of homocysteine, lipoprotein(a) and fibrinogen are accompanied by an increased risk for cardiovascular complications in the general population. All three parameters are markedly elevated in patients with renal disease, a group with a high prevalence and incidence of cardiovascular complications. This review discusses these parameters in such patients in relation to the occurrence of atherosclerotic complications.
在普通人群中,高血浆同型半胱氨酸、脂蛋白(a)和纤维蛋白原浓度与心血管并发症风险增加相关。在肾病患者中,这三个参数均显著升高,该群体心血管并发症的患病率和发病率都很高。这篇综述讨论了此类患者中这些参数与动脉粥样硬化并发症发生情况的关系。