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肯尼亚人颌面部骨肉瘤

Osteosarcoma of the maxillofacial bones in Kenyans.

作者信息

Chindia M L, Guthua S W, Awange D O, Wakoli K A

机构信息

Department of Oral-Maxillofacial Surgery/Oral Pathology-Oral Medicine, Faculty of Dental Sciences, University of Nairobi, Kenya.

出版信息

J Craniomaxillofac Surg. 1998 Apr;26(2):98-101. doi: 10.1016/s1010-5182(98)80047-4.

Abstract

Osteosarcoma (OS) is a highly malignant tumour and is the most common primary neoplasm of bone; although rare, especially in the maxillofacial skeleton. This article presents 14 Kenyan cases of OS of the maxillofacial bones seen between January 1991 and July 1997: 11 in the mandible, two in the maxilla and one in the right zygomatic arch. Patients ranged in age from one week to 50 years (Mean = 29.7), with an equal gender distribution. While pain and rapid swelling were the commonest clinical features, the radiographic and histopathological characteristics were as varied as has been described elsewhere. Generally, effective management of most of the cases was poor due to late presentation for treatment.

摘要

骨肉瘤(OS)是一种高度恶性肿瘤,是最常见的原发性骨肿瘤;尽管在颌面部骨骼中较为罕见。本文介绍了1991年1月至1997年7月间在肯尼亚所见的14例颌面部骨肉瘤病例:11例在下颌骨,2例在上颌骨,1例在右颧弓。患者年龄从1周至50岁不等(平均 = 29.7岁),性别分布均衡。疼痛和迅速肿胀是最常见的临床特征,而影像学和组织病理学特征与其他地方所描述的一样多样。总体而言,由于就诊治疗较晚,大多数病例的有效治疗情况较差。

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