Kalaĭdzhieva M, Vakrilova L, Dinova S
Akush Ginekol (Sofiia). 1997;36(3):29-32.
This retrospective study, performed in University Maternity Hospital "Maĭchin dom"--Sofia for the period 1991-1995, shows that the frequency of congenital malformations among the live born VLBW neonates is approximately 6 times higher than those among newborns, weighing above 1500 g. Central nervous system anomalies occur the first place of the structure of congenital malformations in the first group, followed by anomalies of the cardio-vascular system and polymalformative syndromes. Great malformations are the main reason for dying in the neonatal period in newborns, weighing above 1500 g, while in VLBW infants they come on third place after perinatal asphyxia and intraventricular hemorrhages.
这项回顾性研究于1991年至1995年期间在索菲亚的“Maĭchin dom”大学妇产医院进行,结果显示,极低出生体重(VLBW)活产新生儿的先天性畸形发生率比体重超过1500克的新生儿高约6倍。中枢神经系统异常在第一组先天性畸形结构中位居首位,其次是心血管系统异常和多发畸形综合征。严重畸形是体重超过1500克新生儿在新生儿期死亡的主要原因,而在极低出生体重儿中,严重畸形在围产期窒息和脑室内出血之后位居第三位。