Marinella M A
Department of Internal Medicine, Wright State University School of Medicine, Dayton, OH 45429, USA.
Tumori. 1998 Jan-Feb;84(1):85-6. doi: 10.1177/030089169808400119.
The case of a previously healthy 63-year-old female with metastatic adenocarcinoma to the hypothalamus presenting with central diabetes insipidus is presented. The patient was found to have metastatic disease isolated to her hypothalamus on brain magnetic resonance imaging as well as a water deprivation test consistent with central diabetes insipidus. The patient had a decrease in symptoms of polyuria and polydypsia as well as a decrease in urine volumes after treatment with intranasal vasopressin. Even though a rare occurrence, physicians should consider metastatic adenocarcinoma in patients with recent-onset polyuria and polydypsia.
本文介绍了一例63岁既往健康的女性，患有下丘脑转移性腺癌并表现为中枢性尿崩症。患者经脑磁共振成像检查发现转移性疾病仅局限于下丘脑，且禁水-加压素试验结果符合中枢性尿崩症。经鼻应用血管加压素治疗后，患者多尿和烦渴症状减轻，尿量减少。尽管这种情况罕见，但医生对于近期出现多尿和烦渴症状的患者应考虑转移性腺癌的可能。
