Humbertclaude V T, Coubes P A, Robain O, Echenne B B
Service de Neuropédiatrie, Clinique Saint-Eloi, Montpellier, France.
Pediatr Neurosurg. 1997 Nov;27(5):268-71. doi: 10.1159/000121265.
We report a case with hemimegalencephaly and catastrophic epilepsy treated early at 4 months by functional hemispherectomy. The boy had intractable continuous epilepsy, with seizures every 10 min, hemiparesis and absence of psychomotor acquisition. Three years after hemispherectomy, the boy is seizure free and has a mild psychomotor delay. Hemiparesis and hemianopsia are unchanged. Early hemispherectomy, before 6 months of age, may control severe epilepsy and preserve the development of higher cortical functions in the nonhemimegalencephalic hemisphere.
我们报告了一例患有半侧巨脑症和灾难性癫痫的病例，该患儿在4个月大时接受了功能性大脑半球切除术。该男孩患有顽固性持续性癫痫，每10分钟发作一次，伴有偏瘫且精神运动发育停滞。大脑半球切除术后三年，该男孩不再发作癫痫，仅有轻度精神运动发育迟缓。偏瘫和偏盲情况未变。在6个月龄前进行早期大脑半球切除术，可能控制严重癫痫，并保留非半侧巨脑症半球的高级皮质功能发育。
