Keller C, Brimacombe J
Department of Anaesthesia and Intensive Care Medicine, Leopold-Franzens University, Innsbruck, Austria.
Anesth Analg. 1998 Jun;86(6):1280-2. doi: 10.1097/00000539-199806000-00028.
We compared bronchial mucus transport velocity (BTV), an index of mucociliary clearance, between the laryngeal mask airway (LMA) and the tracheal tube (TT). Forty patients were studied during propofol anesthesia and muscle relaxation with rocuronium. BTV was measured 10 and 60 min after insertion of the airway device by fiberoptic observation of the movement of methylene blue dye injected onto the dorsal surface of the left main bronchus. BTV for the LMA was similar at 10 and 60 min (13.9 +/- 2.0 and 13.6 +/- 2.1 mm/min, respectively). BTV for the TT was significantly faster at 10 min that at 60 min (13.0 +/- 1.4 vs 6.9 +/- 1.2 mm/min, respectively; P < 0.00001). BTV was similar for both devices at 10 min (TT 13.0 +/- 1.4 mm/min versus LMA 13.9 +/- 2.0 mm/min), but was significantly faster for the LMA than for the TT at 60 min (LMA 13.6 +/- 2.1 mm/min versus TT 6.9 +/- 1.2 mm/min; P < 0.00001). We conclude that the LMA impedes mucociliary clearance less than the TT in anesthetized patients. This may have implications for reducing the risk of retention of secretions, atelectasis, and pulmonary infection.
This study compares bronchial mucus transport velocity, an index of mucociliary clearance, in anesthetized patients between two airway devices, the cuffed tracheal tube and the laryngeal mask airway. We have shown that the laryngeal mask airway impairs mucociliary clearance less than the tracheal tube. This may have implications for reducing the risk of retention of secretions, atelectasis, and pulmonary infection.
我们比较了喉罩气道(LMA)和气管导管(TT)之间的支气管黏液运输速度(BTV),这是一种黏液纤毛清除功能的指标。在丙泊酚麻醉并用罗库溴铵进行肌肉松弛的过程中对40例患者进行了研究。通过纤维支气管镜观察注入左主支气管背侧的亚甲蓝染料的移动情况,在插入气道装置后10分钟和60分钟时测量BTV。LMA的BTV在10分钟和60分钟时相似(分别为13.9±2.0和13.6±2.1毫米/分钟)。TT的BTV在10分钟时明显快于60分钟时(分别为13.0±1.4和6.9±1.2毫米/分钟;P<0.00001)。两种装置在10分钟时的BTV相似(TT为13.0±1.4毫米/分钟,LMA为13.9±2.0毫米/分钟),但在60分钟时LMA的BTV明显快于TT(LMA为13.6±2.1毫米/分钟,TT为6.9±1.2毫米/分钟;P<0.00001)。我们得出结论,在麻醉患者中,LMA对黏液纤毛清除功能的阻碍小于TT。这可能对降低分泌物潴留、肺不张和肺部感染的风险具有意义。
本研究比较了两种气道装置(带套囊气管导管和喉罩气道)在麻醉患者中的支气管黏液运输速度,这是一种黏液纤毛清除功能的指标。我们已经表明,喉罩气道对黏液纤毛清除功能的损害小于气管导管。这可能对降低分泌物潴留、肺不张和肺部感染的风险具有意义。