[肠道吸附剂在动脉粥样硬化治疗中的应用]
[Enterosorbents in the treatment of atherosclerosis].
作者信息
Piskun R P, Pentiuk A A, Serkova V K, Polesia T L, Savitskaia E A
机构信息
Vinnitsa State Medical University, Ukraine.
出版信息
Eksp Klin Farmakol. 1998 Mar-Apr;61(2):69-74.
The article lists, characterizes, and discusses the mechanism of the action of endosorbents possessing hypocholesteremic and hypolipidemic effects. Among them are natural endosorbents--food fibers (cellulose, hemicellulose, pectins, gum, mucus, lignin and chitin compounds, etc.); artificial specific affinin and nonspecific carbonic enterosorbents (carbonitrate family, granulated, fibrous), as well as silica (aerosil, polysorb). The effectiveness and pathogenetic expediency of correcting disorders of lipid metabolism in atherosclerosis with enterosorbents is substantiated.
本文列出、描述并讨论了具有降胆固醇和降血脂作用的内吸附剂的作用机制。其中包括天然内吸附剂——食物纤维（纤维素、半纤维素、果胶、树胶、黏液、木质素和几丁质化合物等）；人工特异性亲和吸附剂和非特异性碳质肠吸附剂（碳酸盐类、颗粒状、纤维状），以及二氧化硅（气相二氧化硅、聚山梨醇酯）。肠吸附剂纠正动脉粥样硬化中脂质代谢紊乱的有效性和发病学合理性得到了证实。
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