Yo T, Noguchi I, Kimura T, Sasao M, Amemiya Y, Sekiya H, Kobayashi K
Department of Dental Anesthesiology, School of Dental Medicine, Tsurumi University, Yokohama.
Masui. 1998 May;47(5):611-4.
Patients with Cornelia de Lange syndrome have many anomalies including micrognathia with a small mouth, a high arched palate, and a short neck, which might make laryngoscopy for tracheal intubation difficult during induction of general anesthesia. General anesthesia was performed in a patient with Cornelia de Lange syndrome, and restricted opening of the mouth, which had not been reported previously, was found during laryngoscopy. The possible causes were thought to be temporo-mandibular joint disorders, contracture of the masseter muscle due to injury by self-destructive tendencies, or elogated coronoid process. The potential difficulty with laryngoscopy should be considered for tracheal intubation in a patient with Cornelia de Lange syndrome.
科妮莉亚·德·朗格综合征患者有许多异常情况，包括小颌畸形伴小嘴、高拱腭和短颈，这可能会使全身麻醉诱导期间进行气管插管的喉镜检查变得困难。对一名科妮莉亚·德·朗格综合征患者实施了全身麻醉，喉镜检查时发现了此前未报告过的张口受限情况。可能的原因被认为是颞下颌关节紊乱、由于自残倾向导致的咬肌挛缩或冠突过长。对于科妮莉亚·德·朗格综合征患者进行气管插管时，应考虑到喉镜检查存在潜在困难。
