Chang T C, Tung C C, Hsiao Y L, Chen M H
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Republic of China.
Acta Cytol. 1998 May-Jun;42(3):619-24. doi: 10.1159/000331817.
To determine whether immunoperoxidase staining could be used for differential diagnosis of parathyroid from thyroid origin in fine needle aspirates of suspected parathyroid lesions.
Immunoperoxidase staining of parathyroid hormone and thyroglobulin was performed on aspirated smears from 10 patients with parathyroid lesions (6 of 10 patients also associated with thyroid lesions) and 10 patients with thyroid lesions. All of them had surgical tissue proof of the diagnosis.
Aspirated smears of six patients with parathyroid lesions had strong to moderate staining for parathyroid hormone and negative staining for thyroglobulin. Another four patients with parathyroid lesions had equivocal staining for parathyroid hormone and negative staining for thyroglobulin. All aspirated smears from the 16 thyroid lesions had negative staining for parathyroid hormone and positive staining for thyroglobulin.
Immunoperoxidase staining of parathyroid hormone and thyroglobulin, done for each suspected parathyroid lesion, was helpful in the differential diagnosis of parathyroid vs. thyroid origin.
确定免疫过氧化物酶染色是否可用于在疑似甲状旁腺病变的细针穿刺抽吸物中鉴别甲状旁腺来源与甲状腺来源。
对10例甲状旁腺病变患者（10例患者中有6例还伴有甲状腺病变）和10例甲状腺病变患者的穿刺涂片进行甲状旁腺激素和甲状腺球蛋白的免疫过氧化物酶染色。所有患者均有手术组织确诊依据。
6例甲状旁腺病变患者的穿刺涂片甲状旁腺激素染色呈强至中度，甲状腺球蛋白染色呈阴性。另外4例甲状旁腺病变患者甲状旁腺激素染色不明确，甲状腺球蛋白染色呈阴性。16例甲状腺病变患者的所有穿刺涂片甲状旁腺激素染色呈阴性，甲状腺球蛋白染色呈阳性。
对每个疑似甲状旁腺病变进行甲状旁腺激素和甲状腺球蛋白的免疫过氧化物酶染色，有助于鉴别甲状旁腺来源与甲状腺来源。
