Shet T M, Rege J D
Department of Pathology, T.N. Medical College, Bombay Central, India.
Acta Cytol. 1998 May-Jun;42(3):657-62. doi: 10.1159/000331822.
To analyze fine needle aspirates from tubular adenomas of the breast and elucidate cytologic features unique to these tumors.
Fine needle aspiration (FNA) cytology smears from eight tubular adenomas were reviewed, with special attention given to architectural features and individual cell characteristics. Smears were then compared with those from 25 fibroadenomas and 2 tubular carcinomas for analyzing the distinguishing features.
Aspirates from tubular adenomas revealed cells arranged as small, three-dimensional balls or clusters, tubules of different shapes and less frequently as closely approximated acini. Cells were uniform, with pale cytoplasm, which showed magenta granules in the Giemsa smears from two tumors. Straight tubules, closely approximated acini and intracytoplasmic granules were not seen in aspirates from fibroadenomas. The tubules in tubular adenomas always showed myoepithelial cells and were more open than the angulated tubules of tubular carcinoma.
Tubular adenomas on FNA cytology specifically show cells arranged as small, three-dimensional balls, tubules or closely approximated acini. Cells are uniform and sometimes show intracytoplasmic granules in Giemsa-stained smears.
分析乳腺管状腺瘤的细针穿刺抽吸物，阐明这些肿瘤特有的细胞学特征。
回顾了8例管状腺瘤的细针穿刺（FNA）细胞学涂片，特别关注结构特征和单个细胞特征。然后将涂片与25例纤维腺瘤和2例管状癌的涂片进行比较，以分析鉴别特征。
管状腺瘤的抽吸物显示细胞排列成小的三维球状或团簇状，有不同形状的小管，较少见紧密相邻的腺泡。细胞形态一致，胞质淡染，在2例肿瘤的吉姆萨涂片中可见紫红色颗粒。纤维腺瘤的抽吸物中未见直管、紧密相邻的腺泡和胞质内颗粒。管状腺瘤中的小管总是可见肌上皮细胞，且比管状癌的成角小管更开放。
FNA细胞学检查中，管状腺瘤特异性地显示细胞排列成小的三维球状、小管状或紧密相邻的腺泡状。细胞形态一致，吉姆萨染色涂片中有时可见胞质内颗粒。
