Masuda K, Akutagawa K, Yutani C, Kishita H, Ishibashi-Ueda H, Imakita M
Department of Pathology, National Cardiovascular Center, Osaka, Japan.
Acta Cytol. 1998 May-Jun;42(3):803-6. doi: 10.1159/000331852.
Management after heart transplantation must deal with the twin risks of rejection and infection. Early infection with viral infection, particularly cytomegalovirus (CMV), is becoming more prevalent two to three months after transplantation. To our knowledge, there has been no previous report of human polyomavirus (HPOV) infection after heart transplantation.
A 20-year-old male with a history of Kawasaki disease and who had suffered from severe congestive heart failure after a coronary artery bypass graft, underwent heart transplantation. Urinary cytology demonstrated HPOV infection, the diagnosis of which was established by the immunoperoxidase technique, in situ hybridization and electron microscopy.
The definitive diagnosis of HPOV infection after a heart transplant can be made on urinary cytology.
心脏移植后的管理必须应对排斥和感染这两大风险。移植后两到三个月，病毒感染尤其是巨细胞病毒（CMV）的早期感染正变得越来越普遍。据我们所知，此前尚无心脏移植后人类多瘤病毒（HPOV）感染的报告。
一名20岁男性，有川崎病病史，在冠状动脉搭桥术后出现严重充血性心力衰竭，接受了心脏移植。尿液细胞学检查显示HPOV感染，通过免疫过氧化物酶技术、原位杂交和电子显微镜确诊。
心脏移植后HPOV感染的确诊可通过尿液细胞学检查做出。
