Baccetti T
Department of Orthodontics, University of Florence, Italy.
Angle Orthod. 1998 Jun;68(3):267-74. doi: 10.1043/0003-3219(1998)068<0267:ACSOAD>2.3.CO;2.
The purpose of this study was to reveal patterns of association among seven types of dental anomalies (aplasia of second premolars, small size of maxillary lateral incisors, infraocclusion of primary molars, enamel hypoplasia, ectopic eruption of first molars, supernumerary teeth, and palatal displacement of maxillary canines) in an untreated orthodontic population, ages 7 to 14. The prevalence of associated tooth anomalies in seven groups of 100 subjects selected according to one primarily diagnosed dental anomaly was compared with the prevalence of the examined dental anomalies in a control group of 1,000 subjects. Significant reciprocal associations (p < 0.005) were found among five of the anomalies (aplasia of second premolars, small size of maxillary lateral incisors, infraocclusion of primary molars, enamel hypoplasia, and palatal displacement of maxillary canines), suggesting a common genetic origin for these conditions. Supernumerary teeth appeared to be a separate etiological entity with respect to all other examined tooth anomalies. The existence of associations between different tooth anomalies is clinically relevant, as the early diagnosis of one anomaly may indicate an increased risk for others.
本研究的目的是揭示7至14岁未经治疗的正畸人群中七种牙齿异常（第二前磨牙发育不全、上颌侧切牙过小、乳牙低位咬合、釉质发育不全、第一磨牙异位萌出、多生牙和上颌尖牙腭侧移位）之间的关联模式。将根据一种主要诊断的牙齿异常选出的7组每组100名受试者中相关牙齿异常的患病率，与1000名受试者的对照组中所检查牙齿异常的患病率进行比较。在其中五种异常（第二前磨牙发育不全、上颌侧切牙过小、乳牙低位咬合、釉质发育不全和上颌尖牙腭侧移位）之间发现了显著的相互关联（p < 0.005），这表明这些情况有共同的遗传起源。相对于所有其他检查的牙齿异常，多生牙似乎是一个独立的病因实体。不同牙齿异常之间关联的存在具有临床相关性，因为一种异常的早期诊断可能表明其他异常的风险增加。
