Baccetti T
Department of Orthodontics, The University of Florence, Italy.
Am J Orthod Dentofacial Orthop. 2000 Dec;118(6):608-10. doi: 10.1067/mod.2000.97938.
The occurrence of tooth anomalies in association with failure of the first and second molars to erupt was assessed in a sample of 1520 nonsyndromic subjects with uncrowded dental arches (mean age, 14 years 4 months) and compared with the prevalence rate calculated in a matched control group of 1000 subjects. The tooth anomalies examined included infraocclusion of deciduous molars, palatal displacement of maxillary canines, rotation of maxillary lateral incisors, aplasia of second premolars, and small size of maxillary lateral incisors. Associations among arrested eruption of first and second permanent molars and anomalies in tooth eruption and position (infraoccluded deciduous molars, palatally displaced canines, rotated maxillary lateral incisors) were highly significant (P <. 001). No significant association was found among the occurrence of molar eruption disturbances, aplasia of premolars, and small-sized laterals. These findings point to a common biologic cause for the appearance of failure of eruption of molar teeth and other disturbances in tooth eruption and position, most likely under genetic influence.
在1520名牙弓不拥挤的非综合征受试者（平均年龄14岁4个月）样本中，评估了与第一和第二磨牙萌出失败相关的牙齿异常情况，并与1000名匹配对照组受试者计算出的患病率进行了比较。所检查的牙齿异常包括乳牙磨牙低位咬合、上颌尖牙腭侧移位、上颌侧切牙旋转、第二前磨牙发育不全以及上颌侧切牙过小。第一和第二恒磨牙萌出受阻与牙齿萌出及位置异常（乳牙磨牙低位咬合、尖牙腭侧移位、上颌侧切牙旋转）之间的关联高度显著（P <.001）。在磨牙萌出障碍、前磨牙发育不全和侧切牙过小的发生情况之间未发现显著关联。这些发现表明，磨牙萌出失败以及其他牙齿萌出和位置异常的出现，很可能在遗传影响下，存在共同的生物学原因。
