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[克罗恩病肛门直肠并发症的外科治疗]

[Surgical management of anorectal complications in Crohn disease].

作者信息

Winkler R

机构信息

Abteilung für Allgemeinchirurgie, Chirurgische Klinik, Martin-Luther-Krankenhaus Schleswig.

出版信息

Zentralbl Chir. 1998;123(4):362-7.

PMID:9622895
Abstract

Anorectal manifestations can be expected in about 40% of all patients suffering from Crohn's disease. The frequency increases with extension of disease towards the anal canal. If the rectum is involved, they are obligatory present and contribute to the necessity of a stoma formation. Surgical indication is mostly given, especially in cases with putrid secretion. Primary aim of therapy is the control of peri-anorectal infection by excision of all the inflamed extramural tissue. Wether the underlying fistulas are excised too, depends on their topography to the sphincter system. Fistulas, running distal of the midth of the spincter, are radically excisebal and will definitely heal in over 90%. More than 60% of all fistulous anorectal manifestations belong to this type. Rectovaginal fistulas are provided with fistuloplasty, however healing conditions are problematous and healing will only be gained in about 50%. Fistulas in the upper third of the sphincter or above the sphincteric plane (rectal fistula) are managed by seton drainage of the transmural tract and complete excision of the infected tissue around, so that disease is reduced to its most simply condition. The further aim then is to derive it to cicatrous concretisation, so that infection will not expand again and patients will be free of pain. However this needs prolongation of seton drainage for at least 6 to 12 months.

摘要

在所有克罗恩病患者中,约40%会出现肛肠表现。随着疾病向肛管扩展,其发生率会增加。如果直肠受累,这些表现必然会出现,并导致造口形成的必要性。大多会给出手术指征,尤其是在有恶臭分泌物的情况下。治疗的主要目的是通过切除所有发炎的壁外组织来控制肛周感染。是否同时切除潜在的瘘管,取决于它们与括约肌系统的位置关系。位于括约肌中部远端的瘘管可彻底切除,超过90%肯定会愈合。所有肛肠瘘管表现中,超过60%属于这种类型。直肠阴道瘘采用瘘管成形术治疗,然而愈合情况存在问题,只有约50%能愈合。括约肌上三分之一或括约肌平面以上的瘘管(直肠瘘),通过经壁通道的挂线引流和周围感染组织的完全切除来处理,以使病情简化。接下来的进一步目标是使其形成瘢痕化硬结,这样感染就不会再次扩散,患者也将不再疼痛。然而,这需要将挂线引流延长至少6至12个月。

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