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二氧化碳激光产生烟雾对肺泡的潜在危害。

The potential alveolar hazard of carbon dioxide laser-induced smoke.

作者信息

Kunachak S, Sobhon P

机构信息

Department of Otolaryngology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 1998 Apr;81(4):278-82.

PMID:9623022
Abstract

Carbon dioxide laser is a continuous wave laser, it is well known for its capacity of tremendous smoke production while contact with tissue. Smoke may cause nausea, vomiting, headache and airway irritation. Smoke particles 0.5-2 micrometers in diameter usually travel down the tracheobronchial tree and lodge in the alveoli posing a health hazard. The objectives of this study were to evaluate possible health hazards of carbon dioxide laser smoke in the operating room environment, by determining the size and density of smoke particles also determine the efficacy of surgical masks as a smoke protectant. Ten fresh specimens of papillomatous tissue obtained from the patients were lased by carbon dioxide laser in a continuous mode. The plume generated was collected by 0.45 micrometers pore size microfilter which was attached to the tip of a suction hose connecting the smoke evacuator. The effectiveness of 2 types of commonly used surgical masks were also determined by trapping the smoke after passing through each mask using the same model. Smoke particles were evaluated by scanning electron microscope. The smoke particle density of microfilter that directly trap plume averaged 6 particles/mm2, particles ranging in size from 0.5-27 micrometers, of which 70 per cent were 0.8 micrometers. For the particles trapped after passing through both cotton and paper surgical mask, the size were ranging from 1.6-37 micrometers where 65 per cent were 3.7 micrometers and the particle density average 2.7/mm2. We concluded that the smoke particles derived from carbon dioxide laser application are within the alveolar hazard zone. The conventional surgical masks may not be an effective tool against laser smoke hazard.

摘要

二氧化碳激光是一种连续波激光,因其在与组织接触时会产生大量烟雾而闻名。烟雾可能会导致恶心、呕吐、头痛和气道刺激。直径为0.5 - 2微米的烟雾颗粒通常会顺着气管支气管树向下移动并滞留在肺泡中,对健康构成危害。本研究的目的是通过测定烟雾颗粒的大小和密度,评估手术室环境中二氧化碳激光烟雾可能存在的健康危害,同时也确定手术口罩作为烟雾防护剂的功效。从患者身上获取的10个新鲜乳头状组织标本用二氧化碳激光以连续模式进行照射。产生的烟雾通过连接烟雾抽吸器的吸引导管末端附着的孔径为0.45微米的微滤器收集。还通过使用相同型号的设备在烟雾穿过每种口罩后进行捕获,来确定两种常用手术口罩的有效性。通过扫描电子显微镜对烟雾颗粒进行评估。直接捕获烟雾的微滤器上的烟雾颗粒密度平均为6个颗粒/平方毫米,颗粒大小范围为0.5 - 27微米,其中70%为0.8微米。对于穿过棉布和纸质手术口罩后捕获的颗粒,大小范围为1.6 - 37微米,其中65%为3.7微米,颗粒密度平均为2.7/平方毫米。我们得出结论,二氧化碳激光应用产生的烟雾颗粒处于肺泡危害区域内。传统手术口罩可能不是预防激光烟雾危害的有效工具。

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