威尔士的结核病管理：1986 - 1992年
Management of tuberculosis in Wales: 1986-92.
作者信息
Mathew V, Alfaham M, Evans M R, Adams H, Verrier Jones R, Campbell I, Jenkins T
机构信息
Department of Child Health, Llandough Hospital and Community NHS Trust, Penarth, South Glamorgan.
出版信息
Arch Dis Child. 1998 Apr;78(4):349-53. doi: 10.1136/adc.78.4.349.
OBJECTIVES
To describe the epidemiology of childhood tuberculosis in Wales and to assess the standard of management of patients with tuberculosis.
DESIGN
Retrospective study of data retrieved from case notes and review of radiographs of all identified patients.
SUBJECTS
Forty eight cases of tuberculosis and 10 of tuberculosis chemoprophylaxis in children under 15 years of age, in Wales, between January 1986 and December 1992.
MAIN OUTCOME MEASURES
Management of childhood tuberculosis in Wales compared with the published recommendations of the Joint Tuberculosis Committee of the British Thoracic Society.
RESULTS
Documentation was poor in most of the 48 cases of tuberculosis and only 31 (65%) were formally notified. One third of patients were asymptomatic and were detected by contact tracing; only eight (17%) were culture positive. Only 20% of patients from ethnic minorities had previously been immunised with BCG. Management and chemotherapy varied widely. Few patients were managed jointly by paediatricians and chest doctors. Only 10% completed treatment with a recommended chemotherapy regimen. In 37% of patients treatment was inadequate, and in the remainder either the choice of drugs or the duration of treatment was inappropriate. No patient died, nor had any relapsed by June 1995.
CONCLUSIONS
Very few cases of childhood tuberculosis were managed according to the recommendations of the British Thoracic Society.
目的
描述威尔士儿童结核病的流行病学情况，并评估结核病患者的管理水平。
设计
对从病例记录中检索到的数据进行回顾性研究，并对所有确诊患者的X光片进行复查。
研究对象
1986年1月至1992年12月期间，威尔士15岁以下儿童中的48例结核病病例和10例结核病化学预防病例。
主要观察指标
将威尔士儿童结核病的管理情况与英国胸科学会联合结核病委员会公布的建议进行比较。
结果
48例结核病病例中的大多数记录不完整，仅有31例（65%）得到正式通报。三分之一的患者无症状，通过接触者追踪检测发现；只有8例（17%）培养呈阳性。少数族裔患者中只有20%以前接种过卡介苗。管理和化疗差异很大。很少有患者由儿科医生和胸科医生共同管理。只有10%的患者按照推荐的化疗方案完成治疗。37%的患者治疗不充分，其余患者要么药物选择不当，要么治疗时间不合适。到1995年6月，没有患者死亡，也没有患者复发。
结论
很少有儿童结核病病例按照英国胸科学会的建议进行管理。
Zotero 插件