Goodyear H M, Moore-Gillon J C, Price E H, Larcher V F, Savage M O, Wood C B
Department of Paediatrics, Queen Elizabeth Hospital for Children, London.
Arch Dis Child. 1993 Aug;69(2):229-31. doi: 10.1136/adc.69.2.229.
Childhood tuberculosis is perceived by many as a disease of the past. Experience in a children's hospital serving a deprived population suggested that tuberculosis and other mycobacterial infections were not declining in clinical practice. Fifty three tuberculous and 11 atypical mycobacterial infections were identified between 1978 and 1992. There was no decline in tuberculosis and nine of the 11 atypical infections occurred in the last five years. Altogether 40% of cases of tuberculosis were in non-Asian children; 32% had arrived in the UK or visited family overseas in the previous year; and 38% had a history of tuberculosis contact, usually a close adult relative. Nationally, the previous decline in tuberculosis in all ages has reversed. In the local health districts in London's east end, childhood tuberculosis has also stopped declining and seems to be increasing. It is regrettable that BCG vaccination has been abolished by some districts in the UK, against current recommendations. Childhood tuberculosis is still common in the practice described here, including among children who do not fall into conventionally recognised high risk groups. Inner city dwellers and junior doctors are both highly mobile populations, adding to the risk that paediatricians, particularly those in training, may encounter tuberculosis with little or no previous experience of the condition.
许多人认为儿童结核病是一种过去的疾病。一家为贫困人群服务的儿童医院的经验表明,在临床实践中,结核病和其他分枝杆菌感染并未减少。1978年至1992年间,共确诊了53例结核感染和11例非典型分枝杆菌感染。结核病发病率没有下降,11例非典型感染中有9例发生在过去五年。结核病病例中,40%为非亚裔儿童;32%的儿童在前一年抵达英国或前往海外探亲;38%的儿童有结核病接触史,通常是成年近亲。在全国范围内,各年龄段结核病此前的下降趋势已经逆转。在伦敦东区的当地卫生区,儿童结核病也已停止下降,似乎还在增加。遗憾的是,英国一些地区违背当前建议取消了卡介苗接种。在这里描述的实践中,儿童结核病仍然很常见,包括那些不属于传统上公认的高风险群体的儿童。市中心居民和初级医生都是流动性很强的人群,这增加了儿科医生尤其是实习儿科医生在几乎没有或完全没有结核病既往经验的情况下接触结核病的风险。