Tani J, Yoshida K, Fukazawa H, Kiso Y, Sayama N, Mori K, Aizawa Y, Hori H, Nakasato N, Abe K
Second Department of Internal Medicine, Tohoku University School of Medicine, Sendai, Japan.
Endocr J. 1998 Feb;45(1):117-21. doi: 10.1507/endocrj.45.117.
A 33-year-old woman with signs and symptoms of hypothyroidism, including increased thyroid stimulating blocking antibody (TSBAb) activity, was referred for treatment by her local physician. Her monozygote twin was treated for hyperthyroid Graves' disease 10 years earlier. This case of hyperthyroidism and hypothyroidism in identical twins suggests the involvement of environmental factors in the pathogenesis of autoimmune thyroid diseases.
一名33岁女性出现甲状腺功能减退的体征和症状，包括甲状腺刺激阻断抗体（TSBAb）活性增加，由当地医生转诊接受治疗。她的同卵双胞胎在10年前因甲状腺功能亢进的格雷夫斯病接受过治疗。这对同卵双胞胎中出现甲状腺功能亢进和减退的病例表明，环境因素参与了自身免疫性甲状腺疾病的发病机制。
