Department of Pediatrics, University of Messina, Padiglione NI Policlinico Universitario, Via Consolare Valeria, 98125 Messina, Italy.
Ital J Pediatr. 2013 Jan 30;39:8. doi: 10.1186/1824-7288-39-8.
Aim of this survey is to report the most recent views about Hashimoto's thyroiditis (HT) natural history according to the different presentations. In children presenting with either euthyroidism or subclinical hypothyroidism HT spontaneous course is frequently characterized by a trend towards deterioration of thyroid function, whereas in those presenting with overt hyperthyroidism a definitive resolution of hyperthyroid phase is to be expected. Another possible even though unusual outcome of HT is the conversion to Graves' disease.
本研究旨在根据不同的临床表现报告桥本甲状腺炎(HT)自然史的最新观点。在表现为甲状腺功能正常或亚临床甲状腺功能减退的儿童中,HT 的自发病程常表现为甲状腺功能恶化的趋势,而在表现为显性甲亢的儿童中,甲亢期有望得到明确缓解。HT 的另一种可能的、尽管不常见的结果是向格雷夫斯病转化。