Wilairatana P, Viriyavejakul P, Looareesuwan S, Chongsuphajaisiddhi T
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Ann Trop Med Parasitol. 1997 Oct;91(7):891-6. doi: 10.1080/00034989760662.
Artesunate is a potent antimalarial agent available in oral, parenteral and rectal formulations. Artesunate suppositories rapidly reduce and quickly clear parasitaemias. The rapidity of effect, availability and convenient dosage regimen make artesunate in suppository form a promising treatment for severe falciparum malaria, particularly in rural areas where parenteral formulations are unavailable.
青蒿琥酯是一种高效抗疟药，有口服、胃肠外给药和直肠给药制剂。青蒿琥酯栓剂能迅速降低并快速清除疟原虫血症。其起效迅速、易于获得且给药方案便捷，使得栓剂形式的青蒿琥酯成为治疗重症恶性疟的一种有前景的疗法，尤其是在无法获得胃肠外给药制剂的农村地区。
