Samii A, Lopez-Devine J, Wasserman E M, Dalakas M C, Clark K, Grafman J, Hallett M
Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892-1428, USA.
Muscle Nerve. 1998 Jul;21(7):948-50. doi: 10.1002/(sici)1097-4598(199807)21:7<948::aid-mus16>3.0.co;2-m.
We studied the effects of exercise on motor evoked potentials (MEPs) elicited by transcranial magnetic stimulation in healthy subjects and postpolio patients. Subjects performed repeated sets of isometric exercise until the muscle fatigued. In both groups, the mean MEP amplitude immediately after each exercise set was approximately twice that of the baseline amplitude, indicating similar postexercise facilitation, and after fatigue was approximately half that of the baseline amplitude, indicating similar postexercise depression. We conclude that the intracortical component of central fatigue is normal in postpolio patients.
我们研究了运动对健康受试者和小儿麻痹后遗症患者经颅磁刺激诱发的运动诱发电位（MEP）的影响。受试者进行重复的等长运动组，直到肌肉疲劳。在两组中，每组运动后立即测得的平均MEP波幅约为基线波幅的两倍，表明运动后促进作用相似，而疲劳后约为基线波幅的一半，表明运动后抑制作用相似。我们得出结论，小儿麻痹后遗症患者中枢疲劳的皮质内成分是正常的。
