Tani E, Ersöz C, Svedmyr E, Skoog L
Department of Pathology and Cytology, Karolinska Hospital, Stockholm, Sweden.
Diagn Cytopathol. 1998 Jun;18(6):437-40. doi: 10.1002/(sici)1097-0339(199806)18:6<437::aid-dc10>3.0.co;2-i.
We describe 3 cases of Hodgkin's disease (HD) of unusual suppurative type, which were diagnosed on fine-needle aspirates. The smears were dominated by neutrophils, macrophages, and cellular debris. Only a few large, atypical cells of Hodgkin and Reed-Sternberg type were observed. The differential diagnoses of such smears include infectious mononucleosis, tuberculosis, metastatic lymph node involvement, non-Hodgkin's large-cell anaplastic Ki-1-positive lymphomas, T-cell-rich B-cell lymphomas, and peripheral T-cell lymphomas of mixed type. Immunocytochemistry identified the large atypical cells as CD 30 (BerH2)-positive and negative for CD 45 (LCA) in cytospin material from 2 patients, which allowed a conclusive diagnosis of HD.
我们描述了3例经细针穿刺抽吸诊断为罕见化脓型霍奇金病（HD）的病例。涂片以中性粒细胞、巨噬细胞和细胞碎片为主。仅观察到少数霍奇金和里德-斯腾伯格型的大的非典型细胞。此类涂片的鉴别诊断包括传染性单核细胞增多症、结核病、转移性淋巴结受累、非霍奇金大细胞间变性Ki-1阳性淋巴瘤、富含T细胞的B细胞淋巴瘤以及混合型外周T细胞淋巴瘤。免疫细胞化学鉴定2例患者细胞离心涂片材料中的大的非典型细胞为CD 30（BerH2）阳性且CD 45（LCA）阴性，从而确诊为HD。
