Schlernitzauer D A, Font R L
Arch Ophthalmol. 1976 Sep;94(9):1523-5. doi: 10.1001/archopht.1976.03910040357010.
A 37-year old woman had received multiple radiation treatments between the ages of 6 months and 15 years for an extensive cavernous hemangioma of the left side of the face. At the age of 27 years, a biopsy specimen from a lesion of the left buccal commissure disclosed squamous cell carcinoma arising in chronic radiodermatitis. Multiple cutaneous lesions were excised surgically, and extensive skin grafting of the left side of the face was performed. At the age of 35, she developed a tumor of the left upper and lower eyelids that extended into the orbit, which proved to be a sebaceous gland carcinoma. Following left orbital exenteration, the tumor promptly recurred in the socket. The patient died with widespread metastatic lesions nine months after exenteration. This case, which, to our knowledge, represents the fourth example of postradiation sebaceous gland carcinoma of the eyelids, differs from the previously reported cases in that the radiation therapy had been given for a benign cutaneous condition.
一名37岁女性在6个月至15岁期间因左侧面部广泛的海绵状血管瘤接受了多次放射治疗。27岁时，左侧颊黏膜病变的活检标本显示慢性放射性皮炎中发生了鳞状细胞癌。手术切除了多个皮肤病变，并对左侧面部进行了广泛的皮肤移植。35岁时，她左侧上下眼睑出现肿瘤并蔓延至眼眶，病理证实为皮脂腺癌。左侧眼眶内容物剜除术后，肿瘤在眼眶窝迅速复发。患者在剜除术后9个月因广泛转移病灶死亡。据我们所知，该病例是眼睑放射性皮脂腺癌的第四例，与之前报道的病例不同之处在于，放射治疗是针对一种良性皮肤疾病进行的。
