Goebel J A, Hanson J M, Langhofer L R, Fishel D G
Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO 63110.
Otolaryngol Head Neck Surg. 1995 Feb;112(2):203-9. doi: 10.1016/S0194-59989570237-7.
The currently accepted "gold standard" for rotational testing of the vestibulo-ocular reflex uses a servo-controlled chair for sinusoidal whole-body rotation. Previous work in our laboratory has shown good concordance between conventional rotational chair testing and head-on-body (or "head-shake") testing for gain and phase values of the vestibulo-ocular reflex as recorded and analyzed on our rotational chair system's software. In this article we describe results obtained from 10 normal subjects and 20 patients with reduced caloric responses using a portable system being developed in our laboratory that allows an examiner to generate both whole-body and head-on-body rotational stimuli. Test frequencies within the range 0.25 to 1.0 Hz were chosen for comparison with results obtained by conventional rotational chair testing. Visual conditions for all tests included both visually enhanced vestibulo-ocular reflex (real earth-fixed target) and mentally enhanced vestibulo-ocular reflex (imagined earth-fixed target, in darkness or with vision obscured) paradigms. Our results show general agreement between head-shake and rotational chair testing and both manual whole-body rotation and head-shake testing on our portable system for vestibulo-ocular reflex gain and phase testing, with the largest differences noted at 1.0 Hz. Portable rotational testing was well tolerated by young and elderly subjects alike. We expect manual whole-body rotation and head-shake testing will be useful adjuncts for examining vestibulo-ocular reflex function when more formal rotational chair testing is not possible.
目前被广泛接受的用于前庭眼反射旋转测试的“金标准”是使用伺服控制椅进行正弦全身旋转。我们实验室之前的研究表明，在我们的旋转椅系统软件上记录和分析的前庭眼反射增益和相位值方面，传统旋转椅测试与头部相对于身体（或“摇头”）测试之间具有良好的一致性。在本文中，我们描述了使用我们实验室正在开发的便携式系统对10名正常受试者和20名冷热试验反应降低的患者进行测试所获得的结果，该系统允许检查人员产生全身和头部相对于身体的旋转刺激。选择0.25至1.0 Hz范围内的测试频率，以便与传统旋转椅测试获得的结果进行比较。所有测试的视觉条件包括视觉增强的前庭眼反射（真实的地球固定目标）和心理增强的前庭眼反射（想象中的地球固定目标，在黑暗中或视力受阻时）范式。我们的结果表明，在便携式系统上进行的摇头测试与旋转椅测试以及手动全身旋转和摇头测试在前庭眼反射增益和相位测试方面总体一致，在1.0 Hz时差异最大。便携式旋转测试在年轻和老年受试者中都具有良好的耐受性。我们预计，当无法进行更正式的旋转椅测试时，手动全身旋转和摇头测试将成为检查前庭眼反射功能的有用辅助方法。
