Mikami A, Watanabe T, Motonishi M, Honda H, Kyotani K, Uruha S, Terashima K, Teshima Y, Sugita Y
Department of Neuropsychiatry, Osaka University Medical School, Japan.
Psychiatry Clin Neurosci. 1998 Apr;52(2):216-7. doi: 10.1111/j.1440-1819.1998.tb01038.x.
We investigated the alteration of esophageal pressure (Pes) in 10 patients with upper-airway sleep-disordered breathing (UASDB) and the relationship among Pes, breathing patterns and EEG arousals. Increased negative Pes without apnea or hypopnea, appeared not only in upper airway resistance syndrome but also in obstructive sleep apnea syndrome. This phenomenon produced frequent EEG microarousals leading to sleep fragmentation and daytime sleepiness. Moreover, increased negative Pes occasionally continued for more than 20 min without an EEG arousal, which might be considered to be one of the factors to cause complications of UASDB.
我们研究了10例上气道睡眠呼吸障碍（UASDB）患者的食管压力（Pes）变化以及Pes、呼吸模式和脑电图觉醒之间的关系。在无呼吸暂停或呼吸浅慢的情况下，Pes负值增加不仅出现在上气道阻力综合征中，也出现在阻塞性睡眠呼吸暂停综合征中。这种现象会频繁引发脑电图微觉醒，导致睡眠片段化和日间嗜睡。此外，Pes负值增加偶尔会持续超过20分钟而无脑电图觉醒，这可能被认为是导致UASDB并发症的因素之一。
