Leung S S, Chan Y L, Lam C W, Peng X H, Woo K S, Metreweli C
Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin.
Acta Paediatr. 1998 Apr;87(4):363-7. doi: 10.1080/08035259850156896.
It has been suggested that distribution of body fat has a stronger bearing on health risk than total body fat. Magnetic resonance imaging (MRI) was used to examine the distribution of fat and correlated with body fat assessed by the usual clinical methods-weight, weight-for-height, body mass index (BMI), triceps and subscapular skinfold thickness in 11-y-old Chinese children. Lipid profiles were used as indicators for coronary risk. Eighty-eight subjects had body fat distribution estimated by MRI, while 49 had serum lipids measured. Anthropometric parameters correlated significantly with total fat at the umbilical level measured by MRI (weight: r = 0.90 in boys, 0.75 in girls; BMI: r = 0.94 in boys, 0.87 in girls; percent median weight-for-height: r = 0.90 in boys, 0.79 in girls, triceps skinfold thickness: r = 0.89 in boys, 0.90 in girls; subscapular skinfold thickness: r = 0.93 in boys, 0.88 in girls). Obese subjects had proportionally less visceral fat than subcutaneous fat at umbilical level. Using stepwise multiple regression, predictive factors for high-density lipoprotein cholesterol were BMI in boys and breast-staging in girls. For triglycerides, it was genital staging in boys and for total cholesterol, it was breast-staging in girls. Visceral fat was not a significant determinant of serum lipids.
有人提出，身体脂肪的分布对健康风险的影响比总体脂肪更大。采用磁共振成像（MRI）来检查脂肪分布，并将其与通过常规临床方法评估的身体脂肪进行关联，这些常规临床方法包括11岁中国儿童的体重、身高体重比、体重指数（BMI）、肱三头肌和肩胛下皮褶厚度。血脂谱被用作冠心病风险的指标。88名受试者通过MRI估计身体脂肪分布，49名受试者测量了血脂。人体测量参数与通过MRI测量的脐部水平总脂肪显著相关（体重：男孩r = 0.90，女孩r = 0.75；BMI：男孩r = 0.94，女孩r = 0.87；身高体重中位数百分比：男孩r = 0.90，女孩r = 0.79；肱三头肌皮褶厚度：男孩r = 0.89，女孩r = 0.90；肩胛下皮褶厚度：男孩r = 0.93，女孩r = 0.88）。肥胖受试者在脐部水平的内脏脂肪比例比皮下脂肪少。采用逐步多元回归分析，男孩中高密度脂蛋白胆固醇的预测因素是BMI，女孩是乳房分期。对于甘油三酯，男孩是生殖器分期，对于总胆固醇，女孩是乳房分期。内脏脂肪不是血脂的显著决定因素。
