Oyarzabal M, Aliaga M, Chueca M, Echarte G, Ulied A
Servicio de Endocrinología Pediátrica, Hospital Virgen del Camino, Pamplona, Spain.
Acta Paediatr. 1998 Apr;87(4):387-91. doi: 10.1080/08035259850156959.
A survey was undertaken to evaluate compliance in Spanish patients receiving growth hormone treatment. The 28-item structured questionnaire was designed to collect data on compliance, treatment schedule, device used and instruction received. In total, 473 questionnaires were completed in 17 paediatric endocrine units. Compliance was divided into four categories based on percentage of doses omitted, classified as excellent if 0%, good <5%, fair 5-10% and poor >10%. The level of compliance was excellent in 74.0%, good in 20.1%, fair in 3.4% and poor in 2.5%. Compliance was better in those who injected themselves (p < 0.01), were trained by hospital staff (p < 0.01) and used automatic pens (p < 0.05). Patients using conventional syringes were less likely to comply (p < 0.05). More information on growth hormone treatment was requested by 57.6% of patients. The results indicate that the specialist nurse should spend sufficient time with the patients and relatives to ensure a higher compliance rate.
开展了一项调查，以评估接受生长激素治疗的西班牙患者的依从性。这份包含28个条目的结构化问卷旨在收集有关依从性、治疗方案、使用的器械和所接受指导的资料。17个儿科内分泌科室共完成了473份问卷。依从性根据漏用剂量的百分比分为四类，如果漏用率为0%则为优秀，<5%为良好，5-10%为中等，>10%为差。依从性水平优秀的占74.0%，良好的占20.1%，中等的占3.4%，差的占2.5%。自行注射的患者（p<0.01）、接受医院工作人员培训的患者（p<0.01）以及使用自动笔的患者（p<0.05）依从性更好。使用传统注射器的患者依从性较低（p<0.05）。57.6%的患者要求获取更多有关生长激素治疗的信息。结果表明，专科护士应与患者及其亲属充分交流，以确保更高的依从率。
