火鸡肝脏黄嘌呤脱氢酶。烟酰胺腺嘌呤二核苷酸氧化还原酶活性与功能性酶含量之间的关系。
Turkey liver xanthine dehydrogenase. Relation between nicotinamide-adenine dinucleotide oxidoreductase activity and the content of functional enzyme.
作者信息
Fhaoláin I N, Coughlan M P
出版信息
Biochem J. 1976 Jul 1;157(1):283-5. doi: 10.1042/bj1570283.
Abstract
The turkey liver xanthine dehydrogenase-catalysed oxidation of NADH by Methylene Blue, by ferricyanide or by O2 is not dependent on the integrity of the active-centre persulphide groups. By contrast, the NADH-dichlorophenol-indophenol oxidoreductase and NADH-trinitrobenzenesulphonate oxidoreductase activities are directly proportional to the content of functional enzyme. These findings help to identify the sites of egress of electrons to oxidizing substrates.
摘要
火鸡肝脏中的黄嘌呤脱氢酶催化的NADH被亚甲蓝、铁氰化物或氧气氧化的反应并不依赖于活性中心二硫化物基团的完整性。相比之下，NADH-二氯酚靛酚氧化还原酶和NADH-三硝基苯磺酸盐氧化还原酶的活性与功能性酶的含量成正比。这些发现有助于确定电子向氧化底物流出的位点。
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引用本文的文献
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Stopped-flow spectrophotometric studies on the reaction of turkey liver xanthine dehydrogenase with reducing substrates.
Biochem J. 1978 Apr 1;171(1):83-8. doi: 10.1042/bj1710083.
本文引用的文献
1
Xanthine oxidase and milk flavoprotein: With an Addendum by J. St L. Philpot.
Biochem J. 1939 Oct;33(10):1694-708. doi: 10.1042/bj0331694.
2
On the interaction of the electron acceptor 2,6-dichlorophenolindophenol with bovine milk xanthine oxidase.
J Biol Chem. 1971 Jan 25;246(2):286-93.
3
On the mechanism of inactivation of xanthine oxidase by cyanide.
J Biol Chem. 1970 Dec 25;245(24):6595-8.
4
A comparison of the specificities of xanthine oxidase and aldehyde oxidase.
Arch Biochem Biophys. 1972 Jun;150(2):585-99. doi: 10.1016/0003-9861(72)90078-1.
5
Purification of hepatic xanthine dehydrogenase from chicken fed a high-protein diet.
Biochim Biophys Acta. 1974 Mar 21;341(1):93-8. doi: 10.1016/0005-2744(74)90069-2.
6
Turkey liver xanthine dehydrogenase: properties of the enzyme dependent on the content of functional active sites.
Biochem J. 1974 Nov;143(2):465-8. doi: 10.1042/bj1430465.
7
Turkey liver xanthine dehydrogenase. Reactivation of the cyanide-inactivated enxyme by sulphide and by selenide.
Biochem J. 1974 Nov;143(2):331-40. doi: 10.1042/bj1430331.
8
Nonequivalence of the flavin adenine dinucleotide moieties of chicken liver xanthine dehydrogenase.
J Biol Chem. 1972 Apr 10;247(7):2177-82.
9
The resolution of active and inactive xanthine oxidase by affinity chromatography.
J Biol Chem. 1972 Mar 10;247(5):1597-604.
10
The role of molybdenum in xanthine oxidase and related enzymes. Reactivity with cyanide, arsenite, and methanol.
J Biol Chem. 1969 May 25;244(10):2658-63.
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