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[对疑似肠病儿童通过吸引胶囊和内镜活检钳同时获取的小肠黏膜活检样本的评估]

[Evaluation of small intestine mucosal biopsies obtained simultaneously by suction capsule and endoscopic forceps in children with suspected enteropathy].

作者信息

Cuevas D J, Kawakami E, Patrício F R

机构信息

Depatamento de Pediatria, Escola Paulista de Medicina, Universidade Federal de São Paulo,- EPM-UNIFESP.

出版信息

Arq Gastroenterol. 1997 Oct-Dec;34(4):248-53.

PMID:9629321
Abstract

The aim of the study was to compare biopsy specimens obtained by suction with those obtained by endoscopy morphometrically and histologically in order to evaluate their adequacy for histological interpretation. For this, 23 children with suspected enteropathy underwent upper gastrointestinal endoscopy. For histological evaluation, biopsies were assessed for orientation, depth, length, presence of Brunner's glands and/or lymphoid follicles and presence of artifact. The mucosa total height and villi height were evaluated for morphometric assessment. The results of all the analysed parameters were not statistically significant, except for the presence of Brunner's glands that were most evident in endoscopic biopsies. Although, the suction capsule biopsies and the endoscopic ones were appropriate for histological interpretation in 91.3% respectively, the difference was not statistically significant. Based on the morphometric analysis, the mucosa total height and the villi height values in both biopsy techniques were not statistically significant different. The small intestine mucosal biopsies obtained by endoscopy compared with those obtained by suction capsule were adequate for histological interpretation.

摘要

本研究的目的是对通过抽吸获取的活检标本与通过内镜检查获取的活检标本进行形态学和组织学比较,以评估它们用于组织学解释的充分性。为此,对23名疑似肠病的儿童进行了上消化道内镜检查。为进行组织学评估,对活检标本的方向、深度、长度、布伦纳腺和/或淋巴滤泡的存在情况以及伪像的存在情况进行了评估。对黏膜总高度和绒毛高度进行评估以进行形态学评估。除了布伦纳腺的存在在内镜活检中最为明显外,所有分析参数的结果均无统计学意义。尽管抽吸胶囊活检和内镜活检分别有91.3%适合进行组织学解释,但差异无统计学意义。基于形态学分析,两种活检技术的黏膜总高度和绒毛高度值无统计学显著差异。与通过抽吸胶囊获取的小肠黏膜活检标本相比,通过内镜检查获取的标本足以进行组织学解释。

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