Torres L F, Jacob G V, Reis-Filho J S, de Noronha L
Serviço de Anatomia Pathólogica, Hospital de Clínicas, Universidade Federal do Paraná (HC/UFPR), Curitiba, Brasil.
Arq Neuropsiquiatr. 1997 Dec;55(4):795-800. doi: 10.1590/s0004-282x1997000500017.
Tumours of central nervous system (CNS) represent the second most frequent malignancy in children under 15 years of age but are the commonest cause of death. The authors present the epidemiologic and histopathologic analysis of 623 primary tumours of CNS occurring during the period 1990 to 1996 in paediatric patients. In this period 3318 biopsies of CNS were analyzed. In this total were included 623 paediatric tumours (18 7%). The age of patients ranged from 5 months to 15 years, 325 tumours occurred in males and 298 in females. The majority affected the posterior fossa. The majority of paediatric neoplasias were of glial origin (n = 277). The most frequent tumours were: astrocytoma (27.9%), medulloblastoma (9.95%), craniopharyngioma (5.93%), ependymoma (4.97%) and glioblastoma (3.37%).
中枢神经系统（CNS）肿瘤是15岁以下儿童中第二常见的恶性肿瘤，但却是最常见的死亡原因。作者对1990年至1996年期间儿科患者发生的623例原发性中枢神经系统肿瘤进行了流行病学和组织病理学分析。在此期间，共分析了3318例中枢神经系统活检病例。其中包括623例儿科肿瘤（18.7%）。患者年龄从5个月至15岁不等，男性发生325例肿瘤，女性发生298例。大多数肿瘤位于后颅窝。大多数儿科肿瘤起源于神经胶质（n = 277）。最常见的肿瘤为：星形细胞瘤（27.9%）、髓母细胞瘤（9.95%）、颅咽管瘤（5.93%）、室管膜瘤（4.97%）和胶质母细胞瘤（3.37%）。
