[儿童和青少年中枢神经系统原发性肿瘤的流行病学。一项基于人群的研究]

[Epidemiology of primary tumors of the central nervous system in children and adolescents. A population-based study].

作者信息

Staneczek W, Jänisch W

机构信息

Bereich Nationales Krebsregister und Epidemiologie des Zentralinstituts für Krebsforschung der Akademie der Wissenschaften, Berlin.

出版信息

Pathologe. 1994 Aug;15(4):207-15. doi: 10.1007/s002920050047.

DOI:10.1007/s002920050047

PMID:7971795

Abstract

The incidence of primary CNS tumours in children and adolescents (0-20 years of age) was investigated for the time period 1970-1989 using the records of the East German National Cancer Registry. 2906 such tumors were registered. 93.2% of them were histopathologically confirmed. The incidence was 31.0/1,000,000 for the male and 25.9 for the female population. 2719 (93.6% of all tumours) were intracranially and only 187 (6.4%) intraspinally situated. The incidence of the CNS tumours increased during the time period of the investigation. This increase was more pronounced in the male and less in the female population. The most common tumour types were gliomas (38.7% of all registered CNS tumours), medulloblastomas (14.0%) and ependymomas (10.9%). 130 primary CNS tumours occurred in infants (less than 1 year of age). Among these tumours were 21 ependymomas and 21 choroid plexus tumours.

摘要

利用东德国家癌症登记处的记录，对1970年至1989年期间儿童和青少年（0至20岁）原发性中枢神经系统肿瘤的发病率进行了调查。共登记了2906例此类肿瘤。其中93.2%经组织病理学确诊。男性发病率为31.0/1,000,000，女性为25.9/1,000,000。2719例（占所有肿瘤的93.6%）位于颅内，仅187例（6.4%）位于脊髓内。在调查期间，中枢神经系统肿瘤的发病率有所上升。这种上升在男性中更为明显，在女性中则相对较小。最常见的肿瘤类型是胶质瘤（占所有登记的中枢神经系统肿瘤的38.7%）、髓母细胞瘤（14.0%）和室管膜瘤（10.9%）。130例原发性中枢神经系统肿瘤发生在婴儿（小于1岁）中。这些肿瘤中有21例室管膜瘤和21例脉络丛肿瘤。