Marshman W E, Lyons C J
Ophthalmology Unit, British Columbia's Children's Hospital, Vancouver, Canada.
Aust N Z J Ophthalmol. 1998 May;26(2):161-3. doi: 10.1111/j.1442-9071.1998.tb01534.x.
To highlight an unusual organism causing a unilateral endophthalmitis by transplacental spread.
We report a case of Plesiomonas shigelloides endophthalmitis, presenting in a newborn, with co-existing septicaemia and meningitis. There was a significant maternal history of diarrhoea associated with the ingestion of oysters 2 weeks prior to delivery.
The endophthalmitis was treated with parenteral antibiotics and topical mydriatics with complete resolution, although subsequent assessment of the affected eye suggests a poor visual outcome.
Endophthalmitis in the newborn is an unusual clinical finding and usually presents with other manifestations of bacteraemia. Plesiomonas shigelloides is fortunately an infrequent cause of neonatal infection, but is associated with a high degree of morbidity and mortality. We postulate that this neonate acquired P. shigelloides via the transplacental route, and suggest that this organism be included in the list of 'other' causes of transplacental infection that has been abbreviated to 'O' in the acronym 'TORCH'.
强调一种通过胎盘传播导致单侧眼内炎的罕见病原体。
我们报告了一例新生儿志贺邻单胞菌性眼内炎病例，同时伴有败血症和脑膜炎。产妇在分娩前2周有明显的腹泻病史，与食用牡蛎有关。
眼内炎采用静脉抗生素和局部散瞳剂治疗，炎症完全消退，尽管对患眼的后续评估显示视力预后较差。
新生儿眼内炎是一种不常见的临床发现，通常伴有菌血症的其他表现。幸运的是，志贺邻单胞菌是新生儿感染的罕见病因，但与高度的发病率和死亡率相关。我们推测该新生儿通过胎盘途径感染了志贺邻单胞菌，并建议将该病原体列入经胎盘感染的“其他”病因清单中，在首字母缩略词“TORCH”中已缩写为“O”。
