Brazier J S
Anaerobe Reference Unit, Public Health Laboratory, University Hospital of Wales, Heath Park, Cardiff, UK.
J Antimicrob Chemother. 1998 May;41 Suppl C:47-57. doi: 10.1093/jac/41.suppl_3.47.
Clostridium difficile is normally a harmless environmental bacterium but, under certain circumstances, it can cause hospital outbreaks of disease. To understand the disease epidemiology, outbreaks have been investigated by many different methods. The phenotypic and genotypic approaches to typing are reviewed here and the epidemiology of C. difficile-associated disease is elucidated in light of recent information.
艰难梭菌通常是一种无害的环境细菌，但在某些情况下，它可导致医院内疾病暴发。为了解疾病流行病学，已通过多种不同方法对暴发进行了调查。本文回顾了用于分型的表型和基因型方法，并根据最新信息阐明了艰难梭菌相关性疾病的流行病学。
