Popova T N, Pinheiro de Carvalho M A
Department of Plant Physiology and Biochemistry, Voronezh State University, 394693 Voronezh, Russian Federation.
Biochim Biophys Acta. 1998 May 27;1364(3):307-25. doi: 10.1016/s0005-2728(98)00008-5.
The relevance of citrate and isocitrate metabolism in plants is discussed in connection with the different pathways for their conversions. The routes for citrate and isocitrate conversions are incorporated into the system of cross-linked metabolic processes and may provide carbon skeletons for nitrogen assimilation and reducing equivalents for biosynthetic reactions, support the functioning of the glyoxylate cycle and play an important role in the TCA and energy metabolism as a whole. The possibility of the coupling of citrate and isocitrate metabolism with various electron transport systems is discussed from the point of view of the efficiency of the balancing cellular NAD(P)H/NAD(P)+ and ATP/ADP ratios. The role of citrate and isocitrate and their derivations as potent effectors of some enzymes is considered. Special attention is paid to the enzymes associated with citrate and isocitrate metabolism and to the mechanisms which regulate their activity. The possibilities of the coordination of the main processes of energy and biosynthetic metabolism at the level of citrate and isocitrate distribution are discussed.
结合柠檬酸和异柠檬酸转化的不同途径，讨论了它们在植物代谢中的相关性。柠檬酸和异柠檬酸的转化途径融入了交联代谢过程系统，可为氮同化提供碳骨架，为生物合成反应提供还原当量，支持乙醛酸循环的功能，并在整个三羧酸循环和能量代谢中发挥重要作用。从平衡细胞中NAD(P)H/NAD(P)+和ATP/ADP比率的效率角度，讨论了柠檬酸和异柠檬酸代谢与各种电子传递系统偶联的可能性。考虑了柠檬酸和异柠檬酸及其衍生物作为某些酶的有效效应物的作用。特别关注与柠檬酸和异柠檬酸代谢相关的酶及其调节活性的机制。讨论了在柠檬酸和异柠檬酸分布水平上协调能量和生物合成代谢主要过程的可能性。
