Nuttall T J, French A T, Cheetham H C, Proctor F J
Royal (Dick) School of Veterinary Studies, Summerhall, Edinburgh.
J Small Anim Pract. 1998 May;39(5):237-9. doi: 10.1111/j.1748-5827.1998.tb03641.x.
To evaluate the efficacy of fipronil in controlling trombiculid infestations, 18 dogs and three cats infested with Trombicula autumnalis larvae were treated monthly from examination to the end of the Trombicula season (range one to four months) with a 0.25 per cent fipronil spray applied to the whole body, with particular emphasis on the feet, face, ears, perineum and tail. No other antiparasite measures were used. Follow-up was by clinical examination and telephone interview until the end of the Trombicula season (range one to four months). No adverse effects were seen. Monthly treatment controlled trombiculids in 15 dogs. In two dogs localised pedal reinfestations were controlled with additional local application of fipronil to the feet every 14 days. In one dog therapy was of no benefit. In the three cats, treatment was initially effective, but generalised infestations recurred after seven to 10 days. Fipronil is a safe and effective treatment for trombiculid infestations in dogs. Residual activity lasts for 14 to 30 days. Further studies are required to examine the apparent short duration of efficacy in cats.
为评估氟虫腈对恙螨感染的控制效果，对18只感染秋恙螨幼虫的犬和3只猫，从检查时起至恙螨季节结束（时长1至4个月）每月进行一次全身0.25%氟虫腈喷雾治疗，特别着重于足部、面部、耳部、会阴和尾部。未采取其他抗寄生虫措施。通过临床检查和电话随访至恙螨季节结束（时长1至4个月）。未观察到不良反应。每月治疗控制了15只犬的恙螨感染。2只犬足部局部再次感染通过每14天额外局部应用氟虫腈于足部得到控制。1只犬治疗无效。3只猫治疗最初有效，但7至10天后全身感染复发。氟虫腈是犬恙螨感染的一种安全有效的治疗方法。残留活性持续14至30天。需要进一步研究以考察其在猫身上明显较短的疗效持续时间。
