• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

某些O-(5-芳基-1,2,4-三唑-3-基-乙基)苯甲醛肟和O-(5-芳基-1,3,4-恶二唑-2-基-乙基)苯甲醛肟的合成、亲脂性及抗菌性能

Synthesis, lipophilicity and antimicrobial properties of some O-(5-aryl-1,2,4-triazol-3-yl-ethyl)benzaldoximes and O-(5-aryl-1,3,4-oxydiazol-2-yl-ethyl)benzaldoximes.

作者信息

Papakonstantinou-Garoufalias S, Marakos P, Tsantili-Kakoulidou A, Chytyroglou-Ladas A

机构信息

Department of Pharmacy, University of Athens, Greece.

出版信息

Pharmazie. 1998 May;53(5):300-2.

PMID:9631499
Abstract

The synthesis of benzaldehyde oximethers with suitably substituted 1,2,4-triazoles and 1,3,4-oxadiazoles from the corresponding benzaldoximes is described. The lipophilicity of the compounds was measured as well as their antimicrobial and antifungal activity in vitro. Certain compounds showed relatively significant activity against Bacillus subtilis.

摘要

描述了由相应的苯甲醛肟合成带有适当取代基的1,2,4-三唑和1,3,4-恶二唑的苯甲醛肟醚。测定了这些化合物的亲脂性以及它们的体外抗菌和抗真菌活性。某些化合物对枯草芽孢杆菌显示出相对显著的活性。

相似文献

1
Synthesis, lipophilicity and antimicrobial properties of some O-(5-aryl-1,2,4-triazol-3-yl-ethyl)benzaldoximes and O-(5-aryl-1,3,4-oxydiazol-2-yl-ethyl)benzaldoximes.某些O-(5-芳基-1,2,4-三唑-3-基-乙基)苯甲醛肟和O-(5-芳基-1,3,4-恶二唑-2-基-乙基)苯甲醛肟的合成、亲脂性及抗菌性能
Pharmazie. 1998 May;53(5):300-2.
2
[Synthesis and antibacterial activity of 3-(4-amino-5-methyl-s-triazol-3-sulfanyl)-1-phenyl-propan-1-one O-(5-substituted phenyl-[1,3,4] oxadiazol-2-methyl)-oximes].
Yao Xue Xue Bao. 2006 Dec;41(12):1188-92.
3
Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies.新型磺胺-1,2,4-三唑、1,3,4-噻二唑和 1,3,4-噁二唑的合成，作为潜在的抗菌和抗真菌剂。生物评价和构象分析研究。
Bioorg Med Chem. 2012 Feb 15;20(4):1569-83. doi: 10.1016/j.bmc.2011.12.031. Epub 2011 Dec 30.
4
Synthesis and antibacterial studies of a new series of 1,2-bis(1,3, 4-oxadiazol-2-yl)ethanes and 1,2-bis(4-amino-1,2, 4-triazol-3-yl)ethanes.新型1,2-双（1,3,4-恶二唑-2-基）乙烷和1,2-双（4-氨基-1,2,4-三唑-3-基）乙烷系列的合成与抗菌研究
Eur J Med Chem. 2000 Feb;35(2):267-71. doi: 10.1016/s0223-5234(00)00154-9.
5
Synthesis and antimicrobial activity of novel sulfone-linked bis heterocycles.新型砜连接双杂环的合成与抗菌活性
Eur J Med Chem. 2008 May;43(5):917-24. doi: 10.1016/j.ejmech.2007.06.011. Epub 2007 Jul 6.
6
Synthesis and antimicrobial activity of pyrimidinyl 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles.嘧啶基 1,3,4-噁二唑、1,3,4-噻二唑和 1,2,4-三唑的合成及抗菌活性。
Eur J Med Chem. 2018 Feb 10;145:1-10. doi: 10.1016/j.ejmech.2017.12.067. Epub 2017 Dec 21.
7
[Synthesis and antibacterial activity of 3-(5-substituted phenyl-[1,3,4] oxadiazole-2-yl-methylenethio)-5-pyridin-3-yl-[1,2,4] triazole-4-yl-amines].3-(5-取代苯基-[1,3,4]恶二唑-2-基亚甲基硫代)-5-吡啶-3-基-[1,2,4]三唑-4-基胺的合成与抗菌活性
Yao Xue Xue Bao. 2005 Apr;40(4):337-9.
8
Synthesis and antimicrobial testing of certain oxadiazoline and triazole derivatives.某些恶二唑啉和三唑衍生物的合成及抗菌测试
Pharmazie. 1983 Dec;38(12):833-5.
9
Synthesis of novel 8-hydroxy quinolin based 1,3,4-oxadiazoles and S-substituted 1,2,4-triazole derivatives and evaluation of their anti-inflammatory, analgesic, ulcerogenic and anti-microbial activities.新型 8-羟基喹啉基 1,3,4-噁二唑和 S-取代 1,2,4-三唑衍生物的合成及其抗炎、镇痛、致溃疡和抗菌活性评价。
Med Chem. 2011 Nov;7(6):663-73. doi: 10.2174/157340611797928334.
10
Synthesis, characterization and antimicrobial activity of some substituted 1,2,3-triazoles.一些取代的1,2,3 - 三唑的合成、表征及抗菌活性
Eur J Med Chem. 2005 Nov;40(11):1173-8. doi: 10.1016/j.ejmech.2005.02.013. Epub 2005 Jun 24.

引用本文的文献

1
On constitutional isomers and tautomers of oxadiazolones and their mono- and disulfur analogues (CHNXY; X, Y = S, O).关于恶二唑酮及其单硫和二硫类似物（CHNXY；X、Y = S、O）的构造异构体和互变异构体
Comput Theor Chem. 2013 Feb 1;1005:35-44. doi: 10.1016/j.comptc.2012.11.003. Epub 2012 Nov 29.