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接受经皮腔内冠状动脉成形术的单支冠状动脉高度狭窄患者心绞痛的起源。

Origin of angina pectoris in patients with high-grade single-vessel coronary artery stenosis undergoing percutaneous transluminal coronary angioplasty.

作者信息

Vrachatis A D, Alpert M A, Nikas D J, Dernellis J M, Georgulas V P, Kafkas N V, Deftereos S G, Zacharoulos A A

机构信息

Department of Cardiology, Athens General Hospital, Greece.

出版信息

Am J Cardiol. 1998 Jun 1;81(11):1345-8. doi: 10.1016/s0002-9149(98)00166-0.

DOI:10.1016/s0002-9149(98)00166-0
PMID:9631973
Abstract

This study shows that in patients with subtotal (95% to 99%) coronary artery stenosis, the presence of myocardial ischemia is dictated primarily by the presence and degree of coronary collateral flow, with anterograde flow participating little, if at all, in the origin of myocardial ischemia and angina pectoris. Conversely, in patients with severe but not subtotal coronary artery stenosis (70% to 94%), both reduced anterograde flow and coronary collateralization contribute to the evolution of myocardial ischemia and angina pectoris.

摘要

本研究表明，在冠状动脉狭窄程度为95%至99%的患者中，心肌缺血的发生主要取决于冠状动脉侧支血流的存在及程度，而正向血流对心肌缺血和心绞痛的发生几乎没有影响。相反，在冠状动脉严重但未完全狭窄（70%至94%）的患者中，正向血流减少和冠状动脉侧支循环均会促使心肌缺血和心绞痛的发展。

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