Shetty A K, Homsi O, Ward K, Gedalia A
Department of Pediatrics, Louisiana State University Medical Center, and Children's Hospital of New Orleans 70112, USA.
J Rheumatol. 1998 Jun;25(6):1215-7.
Kawasaki disease (KD) is an acute, febrile, self-limited, multisystem vasculitis that almost exclusively affects young children. We describe a 4-year-old girl with intravenous immunoglobulin (IVIG) resistant KD who developed massive cervical lymphadenopathy and severe respiratory distress. Treatment with intravenous pulse methylprednisolone led to dramatic resolution of her symptoms. We conclude that pulse steroid therapy should be considered in patients with KD complicated by massive lymphadenopathy with life threatening airway obstruction and/or IVIG resistant disease.
川崎病（KD）是一种急性、发热性、自限性的多系统血管炎，几乎只影响幼儿。我们描述了一名4岁患有静脉注射免疫球蛋白（IVIG）抵抗性KD的女孩，她出现了巨大的颈部淋巴结病和严重的呼吸窘迫。静脉注射脉冲甲基强的松龙治疗使她的症状显著缓解。我们得出结论，对于合并有危及生命的气道阻塞的巨大淋巴结病和/或IVIG抵抗性疾病的KD患者，应考虑使用脉冲类固醇疗法。
