Sanjuán Portugal F, Cabrera Chaves T, Yus Gotor C, Gomollón García F
Servicio de Medicina Interna, Hospital Miguel Servet, Zaragoza.
Gastroenterol Hepatol. 1998 Apr;21(4):181-3.
Crohn's disease may involve any area of the digestive tract, but its localization in the duodenum is rare. The clinical, radiological or endoscopic findings may simulate those of peptic ulcer and histologic examination is not diagnostic. In contrast with Crohn's disease of any other localization, the formation of fistulas is exceptional. The authors present one case of duodenal Crohn's disease the unspecific symptomatology of which deviated the original orientation towards the more common diseases. Steroid treatment was not sufficient to control the disease which led to complications with the formation of an enterocutaneous fistula. The association of azathioprine was very effective not only in achieving remission of the process, but also in resolving the complications.
克罗恩病可累及消化道的任何部位,但发生于十二指肠者罕见。其临床、放射学或内镜检查结果可能类似消化性溃疡,组织学检查也不具有诊断性。与发生于其他任何部位的克罗恩病不同,十二指肠克罗恩病很少形成瘘管。作者报告1例十二指肠克罗恩病,其非特异性症状使最初的诊断偏离了更常见的疾病。类固醇治疗不足以控制病情,导致了肠皮肤瘘等并发症。硫唑嘌呤的联合使用不仅在使病情缓解方面非常有效,而且在解决并发症方面也很有效。