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运动神经元病患者评估中的神经根刺激研究

Root stimulation studies in the evaluation of patients with motor neuron disease.

作者信息

Raynor E M, Shefner J M, Ross M H, Logigian E L, Hinchey J A

机构信息

Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

出版信息

Neurology. 1998 Jun;50(6):1907-9. doi: 10.1212/wnl.50.6.1907.

DOI:10.1212/wnl.50.6.1907
PMID:9633760
Abstract

Nerve root stimulation may be employed in patients with motor neuron disease (MND) to rule out motor neuropathy with conduction block. The diagnostic utility of these studies is unknown, in part because the range of amplitude changes across nerve root segments in patients with active neuronal degeneration has not been well studied. We reviewed root stimulation studies in 32 patients (59 nerves) with MND and found segmental amplitude reduction from 0 to 45%, a range similar to values reported for normal subjects; there was no suggestion of conduction block based on our usual criteria.

摘要

神经根刺激可用于运动神经元病(MND)患者,以排除伴有传导阻滞的运动神经病。这些研究的诊断效用尚不清楚,部分原因是对于有活动性神经元变性的患者,其神经根节段的振幅变化范围尚未得到充分研究。我们回顾了32例MND患者(59条神经)的神经根刺激研究,发现节段性振幅降低0%至45%,这一范围与正常受试者报告的值相似;根据我们通常的标准,未提示存在传导阻滞。

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