Marey J, Pego R, Alonso G, López-Facal M S, Marin M, Martínez A, Díaz-Valiño J L
Servicio de Neurologia, Hospital Juan Canalejo, La Coruña, España.
Rev Neurol. 1998 May;26(153):793-9; discussion 799-800.
The authors report a series of 18 patients with myelopathy who were diagnosed of dural arteriovenous fistulas with venous medullary drainage (DFVMd). Purpose was to assess the effectiveness, initial and long term, of embolization, as the initial treatment, using polyvinyl alcohol particles (PVA) and liquid adhesives. N-butyl-cyanoacrylate (NBCA).
Magnetic resonance images were obtained in all patients showing spinal cord tissue changes consistent with an isquemic process secondary to venous hypertension. All 18 patients showed initially an improvement in clinical symptoms, demonstrating previous MR images resolution.
The neurological status of 8 patients subsequently deteriorated with angiographically proven recurrences of their DFVMd. These patients underwent a second successful embolization procedure using NBVA. PVA embolization is long term ineffective and is not without risk. Endovascular treatment is less invasive than surgery, its morbidity is less, and it ensures earlier recovery for the patients. If embolization has failed, surgery can still be done.
We recommend that NBVA embolization be the initial treatment of choice for DFVMd if referring the patient to an experienced interventional Neuroradiology unit is available. Careful clinical and neurologic examination is necessary to establish the diagnosis of DFVMd. Finally, we strongly recommend that patients be followed closely and aggressively. Periodic clinical and radiologic assessments, including MR and spinal angiography, are essential to achieve complete cure.
作者报告了一系列18例患有脊髓病的患者,这些患者被诊断为伴有静脉髓内引流的硬脊膜动静脉瘘(DFVMd)。目的是评估使用聚乙烯醇颗粒(PVA)和液体粘合剂正丁基氰基丙烯酸酯(NBCA)进行栓塞作为初始治疗的短期和长期有效性。
对所有患者进行磁共振成像检查,结果显示脊髓组织变化与静脉高压继发的缺血过程一致。所有18例患者最初临床症状均有改善,先前的磁共振图像显示病变消退。
8例患者的神经状态随后恶化,血管造影证实其DFVMd复发。这些患者接受了第二次成功的使用NBVA的栓塞手术。PVA栓塞长期无效且并非没有风险。血管内治疗比手术侵入性小,发病率低,能确保患者更早康复。如果栓塞失败,仍可进行手术。
如果能将患者转诊至经验丰富的介入神经放射科,我们建议NBVA栓塞是DFVMd的首选初始治疗方法。需要仔细的临床和神经学检查以确诊DFVMd。最后,我们强烈建议对患者进行密切且积极的随访。定期进行临床和影像学评估,包括磁共振成像和脊髓血管造影,对于实现完全治愈至关重要。