Suárez P, Castillo J, Pardellas H, Vadillo J, Lema M, Noya M
Servicio de Neurologia, Complejo Hospitalaria Universitario Hospital Xeral de Galicia, Santiago de Compostela, España.
Rev Neurol. 1998 May;26(153):807-10; discussion 810-1.
Arterial hypertension and hypohyalinosis of the arterias perforantes are said to be the commonest cause of lacunar infarcts, although other etiological factors and anatomo-pathological lesions are described more and more frequently. We designed a study to compare the clinical topographic and prognostic characteristics of patients with hypertensive and non-hypertensive lacunar infarcts.
We selected 51 patients with lacunar infarcts: in 23 (45%) arterial hypertension was the only etiological factor recognized. In 28 (55%) other risk factors (16 diabetes mellitus, 17 cardiopathy, 8 hyperlipemia, 13 cigarette smoking and 11 alcoholism) were seen. We evaluated the form of presentation, the type of infarct and whether this was associated with headache. The degree of defect was determined on admission using the Canadian scale. The size of the infarct was measured on CT or RM, using whichever measurement was greater. The evolution of the condition was determined on the Canadian scale and the index of Barthel after three months.
Age and sex distribution was similar to both groups. Motor hemiparesia was the commonest lacunar syndrome and the distribution was similar. There was no difference in form of onset, association with headache or neurological defect between the hypertensive and non-hypertensive lacunar infarcts. The topographical distribution, the presentation of single or multiple lesions, the size of the infarcts and the prognosis were similar in both groups.
Lacunar infarcts, whether hypertensive or not, show no differences regarding clinical, neuro-radiological or evolutionary characteristics.
尽管越来越频繁地描述了其他病因和解剖病理病变,但动脉高血压和穿通动脉玻璃样变性不足据说仍是腔隙性脑梗死最常见的病因。我们设计了一项研究,以比较高血压性和非高血压性腔隙性脑梗死患者的临床、地形学和预后特征。
我们选择了51例腔隙性脑梗死患者:其中23例(45%)动脉高血压是唯一公认的病因。在28例(55%)患者中发现了其他危险因素(16例糖尿病、17例心脏病、8例高脂血症、13例吸烟和11例酗酒)。我们评估了临床表现形式、梗死类型以及是否伴有头痛。入院时使用加拿大量表确定缺陷程度。梗死灶大小通过CT或磁共振成像(RM)测量,取较大值。三个月后根据加拿大量表和Barthel指数确定病情演变情况。
两组患者的年龄和性别分布相似。运动性偏瘫是最常见的腔隙综合征,其分布也相似。高血压性和非高血压性腔隙性脑梗死在发病形式、是否伴有头痛或神经功能缺损方面没有差异。两组在地形学分布、单发或多发病变表现、梗死灶大小和预后方面相似。
无论是否为高血压性,腔隙性脑梗死在临床、神经放射学或病情演变特征方面均无差异。