Bron A J, Tiffany J M
Nuffield Laboratory of Department of Ophthalmology, University of Oxford, United Kingdom.
Adv Exp Med Biol. 1998;438:281-95. doi: 10.1007/978-1-4615-5359-5_40.
Meibomian gland disease--and, in particular, obstructive meibomian gland disease--makes an important contribution to ocular surface disease, in the form of meibomian keratoconjunctivitis. With improved methods for the study of meibomian oil composition and function, we are moving closer to the possibility of distinguishing the contribution of meibomian deficiency, as opposed to inflammatory events, to this disorder. More importantly, where aqueous tear deficiency and meibomian gland disease coincide in patients with dry eye, we are closer to the possibility of distinguishing their relative contributions to the dry eye state. This has implications for future therapies.
睑板腺疾病——尤其是阻塞性睑板腺疾病——以睑板腺性角结膜炎的形式，对眼表疾病有着重要影响。随着研究睑板腺油脂成分和功能的方法不断改进，我们越来越有可能区分睑板腺功能不全与炎症事件对这种疾病的影响。更重要的是，在干眼患者中，当泪液分泌不足与睑板腺疾病同时存在时，我们越来越有可能区分它们对干眼状态的相对影响。这对未来的治疗具有重要意义。
