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迟发性进行性风疹全脑炎的神经病理学

The neuropathology of progressive rubella panencephalitis of late onset.

作者信息

Townsend J J, Wolinsky J S, Baringer J R

出版信息

Brain. 1976 Mar;99(1):81-90. doi: 10.1093/brain/99.1.81.

DOI:10.1093/brain/99.1.81
PMID:963532
Abstract

The clinicopathological changes in a case of progressive rubella panencephalitis of late onset have been presented. The prominent pathological findings in the brain included diffuse destruction of white matter with perivascular inflammatory cells and gliosis, moderate neuronal loss, numerous amorphous vascular deposits in the white matter and severe generalized cerebellar atrophy. These changes are compared and contrasted with those found in congenital rubella and other latent viral illnesses.

摘要

本文报告了一例迟发性进行性风疹全脑炎的临床病理变化。脑部突出的病理表现包括白质弥漫性破坏伴血管周围炎性细胞浸润和胶质细胞增生、中度神经元丧失、白质中大量无定形血管沉积物以及严重的全身性小脑萎缩。并将这些变化与先天性风疹及其他潜伏性病毒疾病中的变化进行了比较和对照。

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