Zhanel G G, Karlowsky J A, Hoban D J
Department of Medical Microbiology, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.
Diagn Microbiol Infect Dis. 1998 Jun;31(2):343-7. doi: 10.1016/s0732-8893(98)00019-4.
The in vitro activities of six fluoroquinolones were determined against 1482 Enterococcus species isolates collected as part of a 1996 Canadian surveillance study. Clinafloxacin MIC90s were 4 or 8 microg/mL, trovafloxacin and BAY 12-8039 MIC90s were 8 or 16 microg/mL, sparfloxacin MIC90s were 32 microg/mL, and ciprofloxacin and ofloxacin MIC90s were >32 microg/mL for the vancomycin-sensitive Enterococcus faecalis, vancomycin-sensitive Enterococcus faecium, and vancomycin-resistant E. faecium isolates collected.
测定了六种氟喹诺酮类药物对1996年加拿大一项监测研究收集的1482株肠球菌分离株的体外活性。克林沙星的MIC90为4或8μg/mL，曲伐沙星和BAY 12 - 8039的MIC90为8或16μg/mL，司帕沙星的MIC90为32μg/mL，环丙沙星和氧氟沙星对收集的万古霉素敏感粪肠球菌、万古霉素敏感屎肠球菌和万古霉素耐药屎肠球菌分离株的MIC90均>32μg/mL。
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