克林沙星与其他抗菌药物对万古霉素敏感和耐药肠球菌的体外比较活性。
The comparative in vitro activity of clinafloxacin and other antimicrobials against vancomycin-susceptible and vancomycin-resistant enterococci.
作者信息
Itokazu G S, Nathan C, Hariharan R, Kostman J R, Kabins S A, Weinstein R A
机构信息
Department of Pharmacy, Michael Reese Hospital and Medical Center, Chicago, Illinois, USA.
出版信息
Chemotherapy. 1996 Jul-Aug;42(4):235-9. doi: 10.1159/000239449.
The susceptibilities of 50 unique vancomycin-susceptible (n = 15) and vancomycin-resistant (n = 35) enterococci to 6 antimicrobials were compared. Teicoplanin was consistently the most active agent for all strains. Ampicillin and imipenem were active primarily for vancomycin-sensitive Enterococcus faecalis. Clinafloxacin and ciprofloxacin showed poorer activity compared to prior studies, suggesting that the emergence of quinolone resistance is now occurring in enterococci.
比较了50株独特的万古霉素敏感肠球菌（n = 15）和万古霉素耐药肠球菌（n = 35）对6种抗菌药物的敏感性。替考拉宁始终是对所有菌株最有效的药物。氨苄西林和亚胺培南主要对万古霉素敏感的粪肠球菌有活性。与先前的研究相比，克林沙星和环丙沙星的活性较差，这表明肠球菌中喹诺酮耐药性正在出现。
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